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WhoIsJack/README.md

Neural Crest banner image

Heya, I'm Jonas,

a systems biologist who studies how cells self-organize and cooperate to perform sophisticated biological functions, such as building organs during embryonic development. To do this, I combine experiments (mainly zebrafish fluorescence microscopy), computation (including image analysis, data science, & simulations), and theory (from modeling all the way to philosophy). For my computational work I primarily use python.

Currently, I work as a postdoctoral researcher in the Mayor lab at University College London.


πŸ”§ I'm currently (mainly) working on...

  • Studying the interplay of cell shape and cell fate using systems microscopy πŸ”¬πŸŸ
    • My main postdoc project uses the zebrafish neural crest as a model system; more on this soon!
    • In earlier related work I analyzed the cellular architecture of the zebrafish lateral line primordium; see my PhD paper!
    • Two blog posts on systems microscopy for non-experts can be found here and here
  • Developing new conceptual perspectives to understand complex living systems, namely the Core & Periphery (C&P) hypothesis πŸ’₯
    • Read the C&P hypothesis paper here!
    • An accompanying blog post can be found here
  • Automating microscopes to track migratory cell populations πŸ€–πŸ”¬
    • I'm the lead dev of DySTrack (Dynamic Sample Tracking), a recently released open-source python tool for automated tracking of moving samples on common commercial microscopes
    • Find it here: GitHub repo, Documentation, Preprint on bioRxiv

πŸ’‘ My thoughts on...

  • The present and future of developmental biology (blog)
  • Synthetic developmental biology (review)
  • Complex biological systems and optogenetics (review)
  • Systems microscopy and digital tissues (blog)

πŸ“œ Repos associated with my contributions to research papers:


πŸ‘€ Some other repos worth checking out:

  • Bioimage analysis with python; my hands-on, self-explanatory tutorial; a bit aged by now but still good; "vintage", one might say :p
  • tissue_exploder; it's basic but it does look fancy, especially in 3D (see banner below)! :D
  • TrackTree; another pretty visualization; maybe I'll actually need it for a paper one day, at which point I'll definitely update the code...

Links to other profiles: ORCID, Google Scholar, LinkedIn, StackOverflow

Posterior lateral line primordium banner image

Pinned Loading

  1. DySTrack DySTrack Public

    A simple automated feedback microscopy tool for live tracking of moving samples.

    Python 10

  2. python-bioimage-analysis-tutorial python-bioimage-analysis-tutorial Public

    A self-explanatory, hands-on intro to bioimage analysis in python. Slightly outdated but still much liked by learners.

    Jupyter Notebook 98 41

  3. opto-notch-adaptation opto-notch-adaptation Public

    This repository hosts the code for "Desensitisation of Notch signalling through dynamic adaptation in the nucleus" (Viswanathan, Hartmann et al., 2021).

    Jupyter Notebook

  4. data-driven-analysis-lateralline data-driven-analysis-lateralline Public

    This repository hosts the code for "An Image-Based Data-Driven Analysis of Cellular Architecture in a Developing Tissue" (Hartmann et al., 2020).

    Jupyter Notebook 4 2

  5. cavity_expansion cavity_expansion Public

    This repo hosts the code for "Competence for neural crest induction is controlled by hydrostatic pressure through YAP" (Alasaadi et al., 2024).

    Jupyter Notebook 2

  6. tissue_exploder tissue_exploder Public

    Create a nice exploded visualization of segmented cells in a tissue.

    Python 7 1