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An accessible introduction to hyperdimensional computing / vector-symbolic architectures

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HDC tutorial

Author: Michiel Stock (michiel.stock@ugent.be)

This is an accessible tutorial about hyperdimensional computing (HDC), with an emphasis to the life sciences. We start from the basics, explaining the mathematics of high-dimensional spaces, the logic of the operations of HDC and its applications. Everything is supported by interactive examples, where you will:

  • compare amino acids;
  • build a language classifier;
  • compute with colors;
  • learn how to design a transmembrane domain for synthetic biology.

Course material:

Much of this tutorial is based on our review paper:

Stock, M., Criekinge, W.V., Boeckaerts, D., Taelman, S., Haeverbeke, M.V., Dewulf, P., Baets, B.D., 2024. Hyperdimensional computing: A fast, robust, and interpretable paradigm for biological data. PLOS Computational Biology 20, e1012426. https://doi.org/10.1371/journal.pcbi.1012426 (link)

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